Factors Affecting the IVF Success Rate

The primary goal of in vitro fertilization (IVF) is to give a patient the chance to become pregnant by using her own or from a donor’s oocytes (egg cells) and sperm cells from her partner (or from a donor). In order to achieve success in such a complicated process, several factors should be put into consideration.

In Vitro Fertilization, as a fertility treatment,  is a multi-factorial procedure that is reliant on proper timing and accuracy. The probabilities of a successful IVF treatment depend on the following conditions.


It is said that between 24 to 34 years old, women have the highest likelihoods of a successful IVF treatment since this is the age range when women are considered to be most fertile. However, once a woman reaches the age of 40, the success rates decrease. 

The Quality of Egg, Sperm, and Embryo

The value of the oocytes, sperm cells, and the embryos depends on other factors enlisted in this post. Factors like age, ovarian reserve, and stimulation protocol affect both the egg cells’ and embryos’ quality. And if the male partner has fertility issues, then the treatment process success rate will also be affected.

*** In the event that the patient’s egg quality is compromised (because of age and other related factors, the use of a donor egg is an option so as to increase the chances of success).

History of Previous Pregnancy

A couple who have had a successful pregnancy in the past indicates a better/higher chance of a positive pregnancy with in vitro fertilization. On the other hand, a medical history of multiple miscarriages and fertility-related issues could mean a more difficult IVF.

Notable fertility issues are as follows: 

  • Uterine abnormalities
  • Presence of fibroid tumors
  • Ovarian dysfunction
  • Duration of time a couple has had difficulty conceiving.

Controlled Ovarian Stimulation Protocol

These practices outline the kind of fertility medications – how they are administered and the schedule or time when they are given. The goal here is to develop several mature oocytes in the optimism that at least one egg cell will result in pregnancy. The doctor and the patient shall work hand in hand to determine which protocol is most favorable for the patient.

Uterine or Endometrial Receptivity

Just like embryo quality. This factor has a critical role in establishing a healthy pregnancy in successions of assisted reproduction. In turn, there are influences affecting such receptivity. It includes uterine lining thickness, immunological factors, and the outline of uterine cavity.

Embryo Transfer

Some IVF professionals believe that the actual embryo transfer procedure is one of the most essential parts of the whole IVF treatment process. Together with a healthy embryo and successful uterine implantation, a faultless transfer is vital. Any difficulty with timing (and even biological factors) can be harmful to the transfer process.

Patient’s Lifestyle

The patient’s way of life is one factor that is important in creating a thriving, healthy environment for an embryo. If a patient plans to undergo IVF, one should stop smoking and drinking alcohol at least 3 months before the actual IVF procedure. Studies have shown that smoking and drinking alcohol decrease the chances of IVF success. Another lifestyle factor to consider is keeping a healthy weight. It has been shown that obesity would affect how hormones and fertility drugs are processed by the body. Henceforth, it is essential that a patient is able to control her lifestyle, so that these factors can be dynamically amended.

Importance of an IVF Incubator

While it is true that a lot of factors rely on the patient’s side, the use of appropriate fertility technologies is another side of the story. Let us look into the importance of INCUBATORS. The principal function of an incubator within the IVF lab is to deliver a stable environment to improve gamete (egg and sperm) function and embryo development in vitro. In short, it serves as the artificial uterus during the in vitro fertilization process. And so as to achieve this goal, an incubator must be able to regulate several environmental variables such as gas concentrations (O2, and CO2), temperature, humidity, and air particulates.

Esco Medical offers an array of incubators that could help achieve higher IVF success rates. One of these incubators is the MIRI® Multiroom Incubator. The MIRI® is a multiroom incubator for embryo culture in the IVF laboratory with 6 independent chambers. Such design can prevent cross-contamination hence, it will not in any way cause any forms of disturbance to the neighboring chambers even in instances where the lids are opened or closed.

Summary Key Features of MIRI®:

  • Heated Lid: Prevents condensation and enhances temperature regulation and recovery.
  • Heated bottom: Provides direct heat transfer to the cultures through the optimization plate for stable heat regulation.
  • Removable Heating Optimization Plate: With a wide selection of inserts.
  • Multiroom System: Completely individual chambers for easier calibration, faster recovery, less disruption, and prevents cross-contamination
  • Control Panel Buttons and LED Display: A display that can be easily seen from a distance and a control panel that allows easy and intuitive operation.
  • Optional SAFE Sens Integration: For continuous pH monitoring.
  • Mute Button: Temporarily mutes alarm messages and sound for five (5) minutes.

Want to know more about the MIRI® Multiroom Incubator? Download the product’s brochure HERE.